tert-butyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-2,4-dihydroquinoxaline-1-carboxylate
tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2,4-dihydroquinoxaline-1-carboxylate
CAS: 959246-52-7
Molecular Formula: C18H25N3O5
tert-butyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-2,4-dihydroquinoxaline-1-carboxylate - Names and Identifiers
| Name | tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2,4-dihydroquinoxaline-1-carboxylate |
| Synonyms | LogP 4-BOC-7-BOCAMINO-3,4-DIHYDROQUINOXALIN-2-ONE tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2,4-dihydroquinoxaline-1-carboxylate tert-butyl 6-{[(tert-butoxy)carbonyl]aMino}-3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carboxylate tert-butyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-2,4-dihydroquinoxaline-1-carboxylate |
| CAS | 959246-52-7 |
| InChI | InChI=1/C18H25N3O5/c1-17(2,3)25-15(23)19-11-7-8-13-12(9-11)20-14(22)10-21(13)16(24)26-18(4,5)6/h7-9H,10H2,1-6H3,(H,19,23)(H,20,22) |
tert-butyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-2,4-dihydroquinoxaline-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C18H25N3O5 |
| Molar Mass | 363.41 |
| Density | 1.227g/cm3 |
| Boling Point | 476.9°C at 760 mmHg |
| Flash Point | 242.2°C |
| Vapor Presure | 2.94E-09mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.558 |
tert-butyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-2,4-dihydroquinoxaline-1-carboxylate - Introduction
tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, is a compound whose structure contains a 1-piperazinyl group, a keto group and an ester group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C¾ H¾ N¾ O¾
-Molecular weight: 464.57g/mol
-Melting point: about 130-133 degrees Celsius
-Solubility: Dissolved in common organic solvents such as dimethylformamide and dichloromethane
Use:
-Pharmaceutical synthesis: tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, is an organic intermediate compound, often used in pharmaceutical synthesis. It can be used to synthesize a variety of biologically active compounds, such as drugs, pesticides and other biologically active molecules.
Preparation Method:
tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, the preparation can be carried out by the following steps:
1. First, using 1,2-cyclohexanedione as raw material, 2,4-dihydroquinoline -3-one was synthesized by oxidation reduction and substitution reaction.
2.2,4-dihydroquinoline -3-one is reacted with 1-piperazinyl carbonyl chloride to obtain 1-(1-piperazinyl)-2,4-dihydroquinoline -3-one.
3. finally, 1-(1-piperazinyl)-2,4-dihydroquinoline -3-one is reacted with tert-butyl chloroformyl aluminum fluoride, tert-butyl chloroformic acid is added, and esterification reaction is carried out to obtain the final product tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2.
Safety Information:
- tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, the relevant safety information is limited, so it is necessary to follow standard laboratory safety operations when using and handling.
-This compound may be irritating to the eyes, skin and respiratory system, so direct contact should be avoided during operation.
-Take appropriate safety measures during operation, such as wearing protective glasses, gloves and laboratory coats.
-It is recommended to operate in a well-ventilated place and avoid inhaling its vapor or dust.
-When using and storing, keep it away from fire and oxidizing agents, and avoid contact with strong acids or alkalis.
Please note that the above information is for reference only, and correct laboratory operation and safety regulations should be followed when using chemicals. It is advisable to have detailed information on the physical and chemical properties and safety of the compound before use, and to seek professional advice and guidance when required.
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C¾ H¾ N¾ O¾
-Molecular weight: 464.57g/mol
-Melting point: about 130-133 degrees Celsius
-Solubility: Dissolved in common organic solvents such as dimethylformamide and dichloromethane
Use:
-Pharmaceutical synthesis: tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, is an organic intermediate compound, often used in pharmaceutical synthesis. It can be used to synthesize a variety of biologically active compounds, such as drugs, pesticides and other biologically active molecules.
Preparation Method:
tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, the preparation can be carried out by the following steps:
1. First, using 1,2-cyclohexanedione as raw material, 2,4-dihydroquinoline -3-one was synthesized by oxidation reduction and substitution reaction.
2.2,4-dihydroquinoline -3-one is reacted with 1-piperazinyl carbonyl chloride to obtain 1-(1-piperazinyl)-2,4-dihydroquinoline -3-one.
3. finally, 1-(1-piperazinyl)-2,4-dihydroquinoline -3-one is reacted with tert-butyl chloroformyl aluminum fluoride, tert-butyl chloroformic acid is added, and esterification reaction is carried out to obtain the final product tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2.
Safety Information:
- tert-butyl 6-(tert-butoxycarbonylamino)-3-oxo-2, the relevant safety information is limited, so it is necessary to follow standard laboratory safety operations when using and handling.
-This compound may be irritating to the eyes, skin and respiratory system, so direct contact should be avoided during operation.
-Take appropriate safety measures during operation, such as wearing protective glasses, gloves and laboratory coats.
-It is recommended to operate in a well-ventilated place and avoid inhaling its vapor or dust.
-When using and storing, keep it away from fire and oxidizing agents, and avoid contact with strong acids or alkalis.
Please note that the above information is for reference only, and correct laboratory operation and safety regulations should be followed when using chemicals. It is advisable to have detailed information on the physical and chemical properties and safety of the compound before use, and to seek professional advice and guidance when required.
Last Update：2024-04-09 21:32:44
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Product Name: 4-BOC-7-BOCAMINO-3,4-DIHYDROQUINOXALIN-2-ONE Visit Supplier Webpage Request for quotation
CAS: 959246-52-7
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Email: 3008007409@qq.com
Mobile: 18021002903
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CAS: 959246-52-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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